EGFR and cancer: To test this hypothesis, a hospital-based study was performed in which 387 GC cases and 392 cancer-free controls in a high-risk Chinese population were genotyped for seven known SNPs in EGFR exons, namely, rs2227983 A>G, rs2072454 C>T, rs17337023 A>T, rs1050171 G>A, rs1140475 C>T,rs2293347 G>A, and rs28384375 T>C.