Therefore, using quantitative RT-PCR, we first compared mRNA levels of 15 known NF-κB target genes associated with cell proliferation (Cyclin D1, Cyclin E, IL-6, IL-1 and TNFα) and suppression of apoptosis (cIAP1, cIAP2, XIAP, survivin, A20, FasL, Bcl-xL, Bcl-2, TRAF1 and TRAF2) in RelB-positive- and RelB-negative-MM patient samples. The gene discussed is RELB; the disease is Miyoshi myopathy.