RASSF3 is overexpressed in mammary gland of tumor-resistant MMTV/neu mice, and exogenous RASSF3 expression reduces cell viability and induces apoptosis in human breast cancer cell lines so, RASSF3 is considered to be responsible in part for resistance to mammary tumor development in neu transgenic mice [26]. This evidence concerns the gene RASSF3 and neoplasm.