GPT and metabolic dysfunction-associated steatohepatitis: The FIB-4 index, developed by Sterling et al. [26] from a database of 832 HIV/HCV coinfected patients, combines age, AST, ALT and platelet count and has been validated in NASH patients for the detection of fibrosis stages F3 and F4 with an AUROC of 0.802, and NPV and PPV of 90% and 80%, respectively [19].