By contrast, Vaillant et al reported that whereas the tumors from the MMTV-Neu model, identical to that which we investigated, also comprised a relatively minor TIC fraction (∼1%), the TIC could not be similarly separated from the bulk tumor cells using antibodies to CD61, CD29 and CD24, leading these investigators to suggest that these tumors do not follow the cancer stem cell model [19]. The gene discussed is ITGB3; the disease is cancer.