Similarly, we found that IL-17 production by cells from leishmaniasis patients were regulated by IL-10 and IFN-γ Finally, since IL-1β was significantly elevated in IL10SD mice and is critical for IL-17 production in many systems [26]–[29], we assessed the course of infection in Il1r1−/− mice that were treated with anti-IL-10R mAb. The gene discussed is IFNG; the disease is leishmaniasis.