Recently, it has been reported that the expression of E-unit-containing structures recognized by an anti-CS-E phage display antibody, GD3G7 [21, 22], is increased in ovarian and pancreatic cancer tissues, resulting in alterations in tumor growth and tumor cell motility through the regulation of the signaling of vascular endothelial growth factor (VEGF) and the cleavage of CD44, respectively [22, 23]. The gene discussed is VEGFA; the disease is familial pancreatic carcinoma.