Among prostaglandins analyzed, 6k-PGF1α, PGE1, and PGF1α production was increased after infection, and PPAR agonists and cPLA2 antagonist diminished their production after infection; however, both PGE2 and PGF2α production was diminished after infection and increased in treated and infected macrophages. The gene discussed is PPARA; the disease is infection.