CYP2C19 and male infertility: We observed a significant interaction between rs4986894 in CYP2C19 and 4-t-OP on male infertility only among the TC/CC genotype and high 4-t-OP exposure group (Pinter = 8.09×10−7, OR = 17.35, 95%CI = 2.33–129.04).