RRV infection had no effect on CD8+ TCRγδ IEL, which increased as a proportion of total T cells from 19±4% on day 14 post infection to 47±2% on day 21 and 59±1% on day 35 in both mock- and RRV-infected NOD mice (C. Zufferey and B. S. Coulson, unpublished data). The gene discussed is CD8A; the disease is infection.