DEPDC1 and neoplasm: These included Rho-associated, coiled-coil containing protein kinase 1 (ROCK1) which stabilises actin in cells, Rho GTPase activating protein 11A (ARHGAP11A), sema domain immunoglobulin domain (Ig) short basic domain, secreted (semaphorin) 3A (SEMA3A: found in human tumour cell lines) and DEP domain containing 1 (DEPDC1), a transcriptional corepressor (Figure S1).