The number of CD45low/−CD34+ KDR+CD133+ early EPCs in AMI patients was 6-fold higher than that of controls, and 24-fold higher than that of CAD patients (Control vs CAD/AMI, 0.04%±0.03% vs 0.01%±0.01%/0.24%±0.02%, PControl vs CAD < 0.01, PControl vs AMI < 0.01, PCAD vs AMI < 0.01) (Fig. 1A). The gene discussed is PROM1; the disease is coronary artery disorder.