In a case-control study of cervical cancer, we genotyped BRCA1 Pro871Leu (rs799917), BARD1 Pro24Ser (rs1048108) and Arg378Ser (rs2229571) and found that the BRCA1 variant rs799917 TT genotype was associated with a significantly decreased risk of cervical cancer in a recessive genetic model (OR=0.62, 95%CI=0.40-0.95), but this association was not observed for the two BARD1 SNPs[65]. The gene discussed is BRCA1; the disease is cervical cancer.