The stratified analysis of rs3856806 in the PPAR-γ gene showed that a more pronounced reduction in T2DM risks was observed in male and younger individuals (≤50-year-old) carrying the rs3856806TT genotype [OR(95%CI)=0.56(0.33-0.93), 0.25(0.13-0.50), respectively]. Here, PPARG is linked to type 2 diabetes mellitus.