Furthermore, in the stratified analysis, we found that the reduced risk of T2DM associated with rs3856806C>T SNP in the PPAR-γ gene was more pronounced among the elderly (> 50 years old) and obese subjects carrying the CT genotype; similarly, we found that the lower risk of T2DM associated with rs3856806 TT genotype was more pronounced among males and younger subjects (≤50-year-old). The gene discussed is PPARG; the disease is type 2 diabetes mellitus.