However, our survival analyses show that in patients who took sorafenib, PFS time was longer in patients with high expression of c-Met than low expression of c-Met (5.60 months vs. 1.43 months, P = 0.010), suggesting that expression of c-MET may predict the effectiveness of sorafenib treatment in HCC patients. The gene discussed is MET; the disease is hepatocellular carcinoma.