High expression of PDGFR-β was more frequent in patients with AFP > 400 IU/mL than with AFP ≤ 400 IU/mL (28.3% vs. 10.6%, P = 0.029), in patients with multiple tumors than with single tumors (25.0% vs. 6.9%, P = 0.033), and in patients without cirrhosis than with cirrhosis (28.9% vs. 10.4%, P = 0.023). The gene discussed is AFP; the disease is Cirrhosis.