TLR4 and posterior cortical atrophy: Subsequently, Andreani and co-workers showed that LPS stimulation of MAT-LU cells in vitro, before inoculation, inhibited tumour growth in syngeneic rats but not in athymic nude mice, indicating that TLR4 stimulation can elicit the T lymphocyte-mediated immune response against the tumour rather than directly acting on PCa cells 54.