Focusing on miRNA and TLR signalling in cancer, it was recently demonstrated that TLR9 stimulation increases the growth and metastatic features of lung cancer cells via the downregulation of miR-7 and the resulting regulation of phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3)/Akt pathway 27. This evidence concerns the gene PIK3R3 and lung carcinoma.