In breast epithelial tumor cells, the signaling elicited by ANXA1/FPR2 interaction induces an increased level of cyclin D1, which is associated to the activation of the PI3K/Akt/p70S6K pathway [79], and in SKCO-15 colorectal adenocarcinoma, ANXA1 mediates cell invasion via FPR2 [80]. The gene discussed is FPR2; the disease is colorectal adenocarcinoma.