BRD2 and menopause: Presence of stem cells in peri-menopausal ovary and their increase after FSH treatment suggests that stem cells persist and retain the ability to proliferate but menopause sets in due to a compromised microenvironment (somatic niche) which does not allow the stem cells to differentiate and assemble into PF as suggested earlier by our group [19,20,31] and also others [32].