More recently, a variant (rs10865170) that resides in the PPARγ3 promoter region has been described.31 This variant has been implicated in modulating bone growth32 via direct influence on growth factor signaling in bone and child height.33 In our study, we noted a significant association only between rs10865170 in PPARγ and obesity. This evidence concerns the gene PPARG and obesity due to melanocortin 4 receptor deficiency.