BIN1 and centronuclear myopathy: Genetic linkage studies have found X-linked recessive centronuclear myopathy is caused by mutations in the gene MTM1 (encodes protein Myotubularin) [63], whereas autosomal dominant and recessive forms are caused by mutations in DNM2 (encodes protein Dynamin 2) [64] and BIN1 (encodes protein Amphiphysin 2) [65] genes respectively.