Variation in this region has been associated with Parkinson's disease (MAPT, PLEKHM1, NSF, c17orf69) progressive supranuclear palsy (MAPT), celiac disease (WNT3), bone mineral density (CRHR1) (NHGRI GWAS catalog) and intracranial volume [44]. Here, PLEKHM1 is linked to Parkinson disease.