BRCA1 and ovarian cancer: An analysis of the joint associations of rs11651753 and rs17631303 from the two 17q21 loci with ovarian cancer risk for BRCA1 carriers (Stage 1 and 2 samples) revealed that both SNPs remained significant in the model (P-for inclusion = 0.001 for rs11651753, 1.2×10−6 for rs17631303), further suggesting that the two regions are independently associated with ovarian cancer for BRCA1 carriers.