Variation in this region has been associated with Parkinson's disease (MAPT, PLEKHM1, NSF, c17orf69) progressive supranuclear palsy (MAPT), celiac disease (WNT3), bone mineral density (CRHR1) (NHGRI GWAS catalog) and intracranial volume [44]. This evidence concerns the gene WNT3 and Classical progressive supranuclear palsy.