EWSR1 and Ewing sarcoma: Focusing on a group of miRs upregulated following EWS/Fli1 knock-down (miRs 22, 100, 125b, 221/222, 27a, and 29a), they showed that levels of these miRs vary specifically with EWS/Fli1 manipulation, including EWS/Fli1 depletion with different shRNAs and ectopic EWS/Fli1 expression in a heterologous fusion-negative cell line, and that these miRs are underexpressed in Ewing Sarcoma cell lines relative to MSCs.