APOE and aneurysm: To determine the effects of CD14 gene deletion on experimental aneurysm formation, we employed 2 widely accepted yet disparate murine models: (1) intra‐aortic infusion of elastase in CD14+/+ and CD14−/− mice and (2) infusion of AngII via an osmotic minipump in hyperlipidemic apoE−/− mice.20 We chose to examine aortic changes at an earlier point, 14 days, as opposed to the previously published and more common 28‐day experiments.