Univariate analysis (Kaplan-Meier analysis) showed that the median OS time for patients with HCC expressing low levels of GPC3 was 34.3 (95% CI, 25.9–42.7) months, compared with 72.3 (95% CI, 48.3–99.4) months for patients with HCC expressing high levels of GPC3 (p = 0.001; log-rank test; Figure 4A). This evidence concerns the gene GPC3 and hepatocellular carcinoma.