A number of genes such as CCL20, CD36 and IL18RAP individually showed significant correlations with clinical variables in colon cancer such as tumor stage (T1 to T4), lymph node status (N0 to N2), metastasis (M0 or M1), pathological grade (G1 to G4) and Duke stage (A to D) (Figures 3A and 3B). This evidence concerns the gene IL18RAP and neoplasm.