In the first, random sample (n = 150), median age was 43 years (interquartile range [IQR] 38–49 years), 125 (83%) were men, ethnicity was white (n = 98, 65%), black African (n = 20, 13%) or other (n = 32, 21%), route of infection was sex between men (n = 106, 71%), heterosexual sex (n = 36, 24%), intravenous drug use (n = 2, 1.3%), vertical (n = 1, 0.7%) or not known (n = 5, 3.3%), current CD4+ count was median 540 cells/μL (IQR 400–720 cells/μL), nadir CD4+ was median 195 cells/μL (IQR 130–280 cells/μL) and 129 patients (86%) were taking ART, of whom 123 (95%) had VL <50 copies/mL. This evidence concerns the gene CD4 and infection.