There is an association to lymphoma, myeloma, or Kaposi sarcoma, whereas there is close relation with other autoimmune and paraneoplastic phenomena (such as paraneoplastic, amyloidosis, as well as an overlap with POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes) [7]. This evidence concerns the gene MYOM2 and plasma cell myeloma.