Maruyama encapsulated 10B into PEGylated transferrin-armed liposomes for targeted delivery to colon carcinoma xenografts, this led to higher 10B tumor accumulation compared to the free isotope or untargeted liposomes and resulted in superior therapeutic efficacy after irradiation over free isotope or untargeted 10B liposomes [36]. This evidence concerns the gene TF and colon carcinoma.