Coupling of the humanized anti-CD22 antibody targeting the lymphocyte marker CD22 to PEGylated doxorubicin-loaded liposomes increased doxorubicin accumulation in Non-Hodgkin's Lymphoma xenografts and increased survival over untargeted doxorubicin-loaded liposomes [33]. The gene discussed is CD22; the disease is non-Hodgkin lymphoma.