IFNA1 and type 1 diabetes mellitus: Several studies have suggested that IFN-α is involved in the development of T1D; for example, higher levels of IFN-α mRNA and protein were detected in the pancreata of T1D patients than nondiabetic patients [19], and IFN-α treatment in patients with tumors or viral hepatitis is also associated with an increased incidence of T1D [20].