Radioresistance in NSCLC has been associated with loss of p53 function, altered expression of survival proteins such as X-linked inhibitor of apoptosis protein (XIAP) and survivin, activation of phosphoinositide 3-kinase (PI3K)/Akt signaling [3], or overexpression of Pim-1 kinase [4]. This evidence concerns the gene XIAP and non-small cell lung carcinoma.