The results of the present study showed that CD151 was expressed at higher levels in GC cells and tumor tissues than in HGEC cells and nontumor tissues, which is consistent with previous reports on CD151 expression in a variety of tumors, including intrahepatic cholangiocarcinoma, HCC, breast, lung, colon and prostate cancer [15], [19], [20], [21]. This evidence concerns the gene CD151 and intrahepatic cholangiocarcinoma.