TNF and Tinnitus: However, TNF-α mRNA levels were significantly decreased in the cochlea (1.3±0.1 versus 1.9±0.2, p<0.001) and IC (1.4±0.2 versus 2.1±0.2, p<0.001) of the Spirulina group and C-PC group (cochlea: 1.0±0.1 versus 1.9±0.2, p<0.001; IC: 1.0±0.1 versus 2.1±0.2, p<0.001), compared with the tinnitus group (Figure 3).