Recently, our study group found that mRNA expression levels of the NR subtype 2B (NR2B) gene, tumor necrosis factor –α (TNF-α) and interleukine-1β (IL-1β) genes were elevated significantly in the cochlea and in the inferior colliculus (IC) in salicylate-induced tinnitus [5], [6]. Here, GRIN2B is linked to Tinnitus.