TNFSF10 and neoplasm: To determine whether 5,7-dihydroxyflavone in combination with TRAIL could inhibit tumor growth in vivo, HepG2 tumor-bearing mice were treated for 28 days with 5,7-dihydroxyflavone (30 mg/kg/d), TRAIL (10 mg/kg/d), the combination of 5,7-dihydroxyflavone and TRAIL, or vehicle control.