However, in the mice treated with 20 mg/kg pp242, we observed a significant antitumor effect in the (Rev)p27IRES-VEGF control Sultan cells (Figure 6(a), filled squares), whereas the p27IRES-VEGF transfected tumor cells were less sensitivity to the effects of the drug (Figure 6(a), open squares). The gene discussed is VEGFA; the disease is neoplasm.