TS expression was reported in 56% (64/114, semiquantitative) of oesophageal adenocarcinoma [13]; 66% (82/124, ≥20% cytoplasmic immunostaining taken as positive) of stomach cancers [16]; and 61% (19/31, same method as used here) of oesophageal adenocarcinoma [20]. Here, TYMS is linked to esophageal adenocarcinoma.