When comparing CD4+IL17A+ cell numbers as well as the expression of IL17A among CD4+IL17A+ cells between DM1 and healthy group, we found that diabetic type 1 patients had higher frequency as well as the absolute number of CD4+IL17A+ Th17 cells than their healthy counterparts (Figure 2; P = 0.0001 and P = 0.0006, resp). Here, CD4 is linked to type 1 diabetes mellitus.