In our recent studies investigating the therapeutic role of adoptively transferred Th1-like effector cells in patients with ovarian cancer, we reported that autologous IFN-γ-secreting CD4 effector cells used in the treatment of long-term surviving patients co-produced higher levels of CD4 effector cell-derived IL-10 when compared to that of short-term survivors. Here, IFNG is linked to ovarian carcinoma.