CXCR3 and neoplasm: In addition, it induces and upregulates IFN-γ (ifnγ) production but also induces the expression of genes encoding the chemokine receptor CXCR3 and the chemokines CCL3 and CCL4 (Jenner et al., 2009) which are responsible for enhancing the mobilization of select type 1-related immune cell responses to sites of tumor growth.