IL17A and neoplasm: For example, recent studies in the murine system by Huber et al., have shown that both IL-17- and IL-17/IFN-γ-producing Th17 cells express higher surface levels of the IL-10Rα when compared to that Th1 cells and that the potential antitumor or pro-tumor effects of the Th17-mediated inflammatory response can be more readily suppressed by endogenously produced IL-10 (Huber et al., 2011).