RAD50 and ataxia-telangiectasia-like disorder: Ataxia-telangiectasia (A-T, ATM mutation), the related A-T like disease (ATLD, MRE11 mutation), Nijmegen breakage syndrome (NBS, NBS1/NBN mutation) and the more recently identified NBS like disease (NBSLD, RAD50 mutation), all present with similar pathological outcomes in humans (Stracker and Petrini, 2011).