Li et al. (2011) recently demonstrated a role for BM-derived EPCs in stimulating neovascularization and pancreatic cancer growth, with EPCs mobilized by the pancreatic cancer cells, and that targeting the CXCL5/CXCL8/CXCR2 axis impaired EPC mobilization, proliferation, differentiation and neovascularization. This evidence concerns the gene CXCR2 and pancreatic neoplasm.