For example, TP53 is mutated in 10-20% of cases of chronic lymphocytic leukemia (CLL) [7,8], 3-8% of cases of acute myeloid leukemia (AML) [8], less than 3% in acute lymphoblastic leukemia (ALL) [9], and 10-12% cases of multiple myeloma (MM) [10-12]. This evidence concerns the gene TP53 and acute lymphoblastic leukemia.