The leader genes in the top deleted regions contained genes with a known contribution to the pathogenesis of DLBCL, such as CDKN2A , B2M [11], PRDM1 [12], TNFAIP3 [13], and NRXN3, a gene previously noted to be altered in DLBCL [5]. The gene discussed is CDKN2A; the disease is diffuse large B-cell lymphoma.