ROBO2 and chronic myelogenous leukemia, BCR-ABL1 positive: The analysis also singled out ROBO2 (deleted in 9% of cases and mutated in 3%) a candidate tumor suppressor in head and neck cancer [21], and MSR1 (deleted in 22% of cases and mutated in 3%), a gene with tumor suppressor function in leukemia stem cells of chronic myeloid leukemia [22].