SOD1 and metabolic dysfunction-associated steatotic liver disease: Videla et al. [35] correlated hepatic and plasma oxidative stress-related parameters with clinical and histological findings in 31 patients with NAFLD, finding that liver SOD activity decreased in the entire group by 48% compared with the controls (p<0.05) and by 64% in patients with steatohepatitis (n=16) (p<0.05).