Patients are risk stratified according to the identification of several prognostic factors at diagnosis including; level of disease dissemination (defined by the International Neuroblastoma Staging System (INSS)), age, histology, and presence of high-risk genetic features such as amplification of the MYCN proto-oncogene and chromosomal gains (17q) and deletions (11q or 1p) [1,4]. Here, MYCN is linked to neuroblastoma.