Aminotransferases are used, together with the measurement of accessible serum parameters such as glucose, triglyceride, cholesterol, lipoproteins, glucose/insulin levels after tolerance tests, and glycated hemoglobin HbA1c (Table 1), to assess NAFLD diagnosis and to screen children from possible hepatopathy-related metabolic complications, such as MS. The gene discussed is INS; the disease is metabolic dysfunction-associated steatotic liver disease.