CYGB and cancer: An univariate Cox proportional hazard regression analysis showed that cancer-specific survival was significantly lower in patients with Gleason score of 9 or higher (HR: 1.759, 95% CI: 1.151-2.687, P = 0.009), HGB less than 11.5 g/dl (HR: 2.251, 95% CI: 1.261-4.019, P = 0.006), ALP of 350 IU/ml or higher (HR: 2.836, 95% CI: 1.756-4.578, P = 0.00002), or LDH of 500 IU/ml or higher (HR: 2.638, 95% CI: 1.442-4.829, P = 0.002) (Table 3).