In our study we examined the immunoglobulin-like domains D2 and D3, the transmembrane domain and the tyrosine kinase domain of FGFR2, i.e. regions in which the typical mutational hot spots of craniosynostosis syndromes are located, in somatic tumor tissue of sporadic breast cancer patients. This evidence concerns the gene FGFR2 and syndromic craniosynostosis.