CD4 and infection: Compared to our baseline scenario of starting treatment at CD4<350 cells/mm3, prioritizing PrEP will result in 3200 infections averted over 10 years (31% reduction; interquartile range (IQR) 23%–39%), whereas a non-prioritized PrEP strategy will result in just 2333 infections averted (23% reduction; IQR: 16–30%) (Figure 1A, 1E).