For example, BCL11B has been implicated in cell cycle progression by directly repressing the cell cycle inhibitors p21WAF1 [43] and p57KIP2 [41] in microglial cells and SK-N-MC (which were originally characterized as a neuroblastoma cell line, but are in fact a Ewing cell line) cells, respectively. The gene discussed is BCL11B; the disease is neuroblastoma.