A collection of the top 10 up- and bottom 10 down-regulated genes at each time-point post infection made a pool of 19 genes: TNF, HSPA1B, TIMP1, TNFSF13, BAG3, HSPA1A, ANGPTL4, HMOX1, GJA1, CCRL1, HBEGF, CCL3L1, HSPA6, HLA-DOA, MAN2B1, NUDC, HLA-DMB, ENPP1 and PLA2G15 as the most actively down-regulated genes and a pool of 25 genes: RAB7B, IL3RA, LRPAP1, HLA-A, ACVR1, ACE, CD24, MAEA, RAB11A, SOD2, SFTPA1, GPX1, ARPC2, TIAL1, H1FX, H1F0, ATF5, MMP9, BNIP3, LGALS9, CCL2, CCL8, IDO1, S100A6, CXCL6 as the most actively up-regulated genes in cellular processes. The gene discussed is TIMP1; the disease is infection.