Furthermore, we found that RKIP downregulation in cervical cancer cells is able to alter cell cycle distribution, induce higher cellular survival, proliferation, migration and anchorage independent growth in vitro. In contrast, no effects were observed in the tumors growth in vivo, but it was found that RKIP inhibition is associated with higher angiogenic rates in cervical cancer. Here, PEBP1 is linked to cervical carcinoma.